As you get older your reactions slow. Us older people buy a lot of games. Cut us some slack lol
legs0fsteel, via Twitter
Motor (basic)
Issues with precise timing can be alleviated very effectively with a choice of game speed (slowing the entire game down into slow motion).
Cognitive (intermediate)
Difficulty with quickly processing action can be helped by a choice of game speed, allowing more time to work out the breadth of what is going on.
Best practice example: Celeste
Best practice example: SYNSO:CE
Best practice example: Tropico 5
Best practice example: Shoot 1UP (01:10) (video)